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[Mandrake]

Although Seed Collector started the thread quoting the rules and stating his intention to comply with them, I want to give it a little bump with the reminder - discussion of preparation or consumption of illegal compounds is not allowed in the STS Rules, and in the case of Cannabis, discussion about gardening or trading seeds/live cuttings is not allowed.

Someone has expressed their concern that this thread might enter a grey area, so please keep that in mind.

Kind regards,

Mandrake

[Shpongle Lover]

I ask you to explain the comments "Good thing, because it is not correct." and "Cannabinoids alone are most definitely NOT a safe alternative to chemotherapy!"

If the bulk of this evidence suggests different than I am implying, I want to know.

I said may... and I stand by it so far.

I will openly admit some of that stuff is over my head, but please explain where I am wrong.

Sure, I'd be happy to elaborate.  Cannabinoids are not cytotoxic.  They do not kill cancer cells, and therefore they cannot be considered a treatment for any form of cancer in humans that I am aware of.   Certainly not in pancreatic cancer, where the mortality rate is huge, usually greater than 80% at five years.   There are, however, chemotherapeutic agents which DO kill cancer cells, and, if administered alone or in combination with surgery and/or adjuvant radiotherapy (ex:  Hodgkins lymphoma or Pancoast tumor) actual cures are possible.  Cannabinoids do not represent a treatment, and certainly have never been documented to have cured a single human of any form of malignancy.

Cannabis, in many of its forms certainly has a place in medicine.  To say otherwise would deny a huge body of both anecdotal evidence and empiric, double-blind studies.  If we are restricting ourselves to a discussion of cancer, the most commonly cited benefits include a reduction in nausea, increases appetite, and a "remoteness" from the pain of the cancer and the anxiety often attendant with a diagnosis of a terminal illness.

It would appear from the studies cited (so far I've only read two of them thoroughly) that neither propose SUBSTITUTING cannabinoids for a chemotherapeutic agent;  rather, they suggest a possible benefit from a synergistic utilization of cannabinoids use ALONG WITH appropriate chemotherapeutic protocol agents.  I'm fine with that.  I think it deserves further study, and ought to be fast-tracked.

Studies such as those cited tend to cause cognitive dissonance amongst the policy makers.  They are VERY used to viewing scheduled drugs as having no medical benefit.  It is their mantra...the policy they hide behind to keep the prison industry and law enforcement afloat.  You and I both know this is hogwash, but after 50 years and multiple billions of dollars spent on the drug war, and the wrongful incarceration of tens of thousands of US citizens, the likelihood of the politicians admitting they erred is about zero.

S.L.

[Greentoe]

Maybe a combination of marijuana and tabernaemontana divaricata to fight cancer. just found this paper thought it was pretty interesting.
http://www.ajpcr.com/Vol5Suppl4/1309.pdf

[Seed Collector]

Maybe a combination of marijuana and tabernaemontana divaricata to fight cancer. just found this paper thought it was pretty interesting.
http://www.ajpcr.com/Vol5Suppl4/1309.pdf

When I tried to download this pdf, I recieved the message "pageok". Does the link work for you?

Edit: I've tried windows 7, and then I tried Tor.


https://www.dropbox.com/home/Cannabis+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip

^ Cannabis and Cannabinoid Scientific Literature.  [some keywords: cancer, apoptosis, and the word suffix "oma"]

[Sunshine]

I opened it into a new tab then downloaded it just fine. Try a different browser.

[Seed Collector]

https://www.dropbox.com/home/Cannabis+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip

^ Cannabis and Cannabinoid Scientific Literature.  [some keywords: cancer, apoptosis, and the word suffix "oma"]

_________________________________________________________________________________________________________________________________________________________________________________________________________________

http://www.alphagalileo.org/ViewItem.aspx?ItemId=135404&CultureCode=en

"Study shows non-hallucinogenic cannabinoids are effective anti-cancer drugs

14 October 2013 St George's, University of London
 

New research has shown that the non-hallucinogenic components of cannabis could act as effective anti-cancer agents.

The anti-cancer properties of tetrahydrocannabinol (THC), the primary hallucinogenic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited.

The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research.

The team, led by Dr Wai Liu and colleagues carried out laboratory investigations using a number of cannabinoids, either alone or in combination with each other, to measure their anti-cancer actions in relation to leukaemia.

Of six cannabinoids studied, each demonstrated anti-cancer properties as effective as those seen in THC. Importantly, they had an increased effect on cancer cells when combined with each other.

Dr Liu said: “This study is a critical step in unpicking the mysteries of cannabis as a source of medicine. The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising.

“These agents are able to interfere with the development of cancerous cells, stopping them in their tracks and preventing them from growing. In some cases, by using specific dosage patterns, they can destroy cancer cells on their own.

“Used in combination with existing treatment, we could discover some highly effective strategies for tackling cancer. Significantly, these compounds are inexpensive to produce and making better use of their unique properties could result in much more cost effective anti-cancer drugs in future.”

This latest research is part of a growing portfolio of studies into the medicinal properties of cannabis by the research team at St George’s. The next step will be to examine in the laboratory these compounds in combination with existing anti-cancer treatments and study treatment schedules to identify strategies that will maximise their efficacy.

The study examined two forms of cannabidiol (CBD), two forms of cannabigerol (CBG) and two forms of cannabigevarin (CBGV). These represent the most common cannabinoids found in the cannabis plant apart from THC."


Below is the paper's abstract & the pdf is attached to this post. http://www.ncbi.nlm.nih.gov/pubmed/24123005


"Anticancer Res. 2013 Oct;33(10):4373-80.

Enhancing the activity of cannabidiol and other cannabinoids in vitro through modifications to drug combinations and treatment schedules.

Scott KA, Shah S, Dalgleish AG, Liu WM.

Source

Dept of Oncology, Division of Clinical Sciences, St. George's, University of London, 2nd Floor, Jenner Wing, London, SW17 0RE, U.K. w.liu@sgul.ac.uk.

Abstract

Cannabinoids are the bioactive components of the Cannabis plant that display a diverse range of therapeutic qualities. We explored the activity of six cannabinoids, used both alone and in combination in leukaemic cells. Cannabinoids were cytostatic and caused a simultaneous arrest at all phases of the cell cycle. Re-culturing pre-treated cells in drug-free medium resulted in dramatic reductions in cell viability. Furthermore, combining cannabinoids was not antagonistic. We suggest that the activities of some cannabinoids are influenced by treatment schedules; therefore, it is important to carefully select the most appropriate strategy in order to maximise their efficacy.

KEYWORDS:

Cannabinoids, drug combination, drug schedule, leukaemia"


http://norml.org/news/2013/10/17/study-non-psychoactive-plant-cannabinoids-possess-synergistic-anti-cancer-activity-in-leukemia-cell-lines <--- NORML on the topic.

https://www.dropbox.com/home/Cannabis+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip

^ Cannabis and Cannabinoid Scientific Literature.  [some keywords: cancer, apoptosis, and the word suffix "oma"]