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[Mangrove]

The first antibiotics, such as penicillins, cephalosporins (e.g. cephalosporin C) and other families of antibiotics originated in fungi. I was wondering if anyone has experience in culturing such antibiotic-producing fungi and may advise me as to how to go about doing this. I thank you all for your time and help.

[ONandONandON]

some links i found to look at later
'antibiotics extract fungi' search..

https://www.biotechnologynotes.com/antibiotics/penicillin/penicillin-biosynthesis-structure-fermentation-process-and-uses/13843
https://blogs.scientificamerican.com/lab-rat/fighting-bacteria-with-weapons-from-fungi/
https://www.biotechnologynotes.com/antibiotics/streptomycin/streptomycin-structure-biosynthesis-process-and-uses-of-streptomycin-biotechnology/13848
https://www.biotechnologynotes.com/antibiotics/fermentation-of-penicillin-antibiotics-biotechnology/1202
https://www.biotechnologynotes.com/antibiotics/production/production-of-antibiotics-by-fermentation-bacteria-fungi-and-penicillin/13886
https://owlcation.com/stem/Medications-From-Molds-Fungi-and-Health
http://fac.ksu.edu.sa/sites/default/files/group_1-_492_mic.pdf
https://bio.libretexts.org/Bookshelves/Ancillary_Materials/Laboratory_Experiments/Microbiology_Labs/Microbiology_Labs_I/07%3A_Isolation_of_an_Antibiotic_Producer_from_soil
https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2672.2012.05347.x
http://www.saps.org.uk/saps-associates/browse-q-and-a/465-how-can-i-extract-antibiotics-from-lichens
https://www.sciencedaily.com/releases/2020/07/200716120658.htm
https://www.imedpub.com/articles/antimicrobial-producing-microbes-isolated-from-soil-samples-collected-from-nanga-merit-forest-in-sarawak-malaysian-borneo.pdf
https://www.sciencedirect.com/science/article/pii/S1607551X14001387
https://www.nature.com/articles/ja201279
https://aem.asm.org/content/68/3/1211
https://chesci.com/wp-content/uploads/2016/10/V3i10_13_Prabha-et-al_178-182.pdf
https://www.japsonline.com/admin/php/uploads/2866_pdf.pdf
http://www.ambrosiasymbiosis.org/labprotocols/fungal-culture-media/
https://bjbas.springeropen.com/track/pdf/10.1186/s43088-019-0026-8
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0224635
http://tru.uni-sz.bg/tsj/VolumeN9_2/M.D.Makut.pdf
https://www.doomandbloom.net/making-penicillin-at-home/
https://en.wikipedia.org/wiki/Production_of_antibiotics
https://www.sites.google.com/site/lowmoonglowing/penicillin
http://www.ambrosiasymbiosis.org/labprotocols/
https://ijpsr.com/bft-article/antibiotic-production-by-microbes-isolated-from-soil/?view=fulltext
https://ijpsr.com/bft-article/isolation-and-identification-of-antibiotic-producing-microorganisms-from-soil/?view=fulltext
https://ir.unimas.my/id/eprint/6042/1/ANTIMICROBIAL%20ACTIVITY%20OF%20CRUDE%20EXTRACT%20FROM%20ANTIBIOTIC%20PRODUCING%20FUNGI(24pgs).pdf
http://biotech.bio5.org/activities/penicillium
https://www.happypreppers.com/antibiotics.html
https://www.slideshare.net/amjadkhanafridi4all/isolation-of-fungi-from-soil-sample-65179339
http://www.eolss.net/Sample-Chapters/C06/E6-151-08-00.pdf
https://pdfs.semanticscholar.org/4416/db7c7636e22c57a1243f45e1285718dc8744.pdf
https://theconversation.com/natures-first-aid-kit-a-fungus-growing-on-the-side-of-birch-trees-117290
https://microbeonline.com/common-fungal-culture-media-uses/
https://www.pharmatutor.org/articles/production-extraction-and-assay-of-antibiotics-from-bacterial-and-fungal-isolates
https://www.sciencedirect.com/science/article/pii/S2221169116311406
https://www.researchgate.net/publication/311565743_Antimicrobial_activity_of_crude_extracts_prepared_from_fungal_mycelia
https://en.wikipedia.org/wiki/Medicinal_fungi

1 Like Mangrove likes this.

[Mangrove]

Sometimes I wonder who first thought of eating moldy bread in order to treat the black death, how mad said loon must have been to suggest it and how desperate his patients must have been...

1 Like Malak likes this.