Share The Seeds
Botany and Research => Plant Science => Topic started by: Seed Collector on August 17, 2013, 12:40:47 AM
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I think we should have a section labeled "science".
STS is particularly focused on species with therapeutic, medicinal and/or psychoactive properties - species with ethnological significance.
I intend to follow the rules here. There are a couple of rules that should be remembered for this thread:
*No Discussion of Illegal Activities. This includes topics like trading or smuggling illegal goods and materials, and discussions about procuring, preparing or consuming scheduled compounds.
*No Extraction Talk. Discussing methods of extraction of psycho-active substances from plant materials is not allowed in STS.
Please spread all the information contained here around as much as possible; Please download and distribute.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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"Scream 'till the walls fall; dissolve all the limits" -- Flobots.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
That is most of the relevant information that I have.
^ Share Those Seeds ;)
Time to get this situation changed, so spread the word.
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Wow! Thanks for this! :)
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Wow. The study showing the benefits of the combined treatment of Gemcitabine with cannabinoids in inhibiting the growth of
human pancreatic tumor cells really got my attention.
Awesome information.
S.L.
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Wow. The study showing the benefits of the combined treatment of Gemcitabine with cannabinoids in inhibiting the growth of
human pancreatic tumor cells really got my attention.
Awesome information.
S.L.
Thank you for checking it out.
I have known several people that found out they had cancer. Two individuals are my neighbors; one has approximately 5 places in his spine that have been damaged by cancer, yet could not get any cannabinoid treatment prescribed, nor recommended (if he were to desire such option). My state is not a medical cannabis state, and my state also does not even allow for the "medical necessity legal defense". only jury nullification, and that is not a preferred option for a cancer patient.
Spreading these pdf's will go a long way toward improving this situation for others.
In America approximately 1/2 of one gender gets cancer, and 1/3 of the other gender gets cancer (so I've read).
Cannabinoids could be a safe alternative to chemotherapy <--- That is not medical advice.
I believe only if people look at these studies will they truly see the importance of such a medicine.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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Cannabinoids could be a safe alternative to chemotherapy <--- That is not medical advice.
Good thing, because it is not correct. If you read the study you will find that the real advantage of the utilization of adjuvant cannabinoids is that certain cell lines are particularly resistant to Gemcitibine. These show a marked increase in sensitivity to the drug with the addition of cannabinoids. Consequently, if you are unlucky enough to have that particular tissue type tumor, the addition of cannabinoids MAY help. Cannabinoids alone are most definitely NOT a safe alternative to chemotherapy!
Further reality check: This study was done in mice. While they are a good human analog, they are most decidedly NOT human, and AFAIK, there have not been any human trials showing any benefit... yet. This study, and others like it will most likely result in an eventual human trial. Because of ethical concerns, medicine has traditionally been, and will likely continue to be, one of the slowest progressing areas in all of science. :(
S.L.
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It's gonna be really hard to get the funding for a study on cannabinoids effects on tumors involving people when it's illegal on the federal level here in the USA... those studies will probably be started in other countries first, unless one of the states like Colorado or Washington can preform a study involving humans.
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Many illegal substances can be prescribed and studied here (though likely difficult).
Since Cannabis and cannabinoids are Schedule I substances, they are claimed to be "of no currently accepted medicinal value", and it is harder to do studies of these substances; even harder to study than more dangerous drugs. "of no currently accepted medicinal value" is clearly not really the case, even if I don't go into the cannabinoid treatment of seizures.
There are enough studies already done about anti-tumor effects of cannabinoids, and seizure treatment with cannabinoids to change the minds of almost any person.
Please make with the downloading.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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Please note that it cannot be oversimplified, for that would undermine the cause. Below is my official "bump".
I was just pointing out 1 of the best points I can for why I do not find the following statement valid (the official position) : "there is no currently accepted medical use for cannabis/cannabinoids" <-- I do not find that valid, and I don't think others would either if they did see the evidence. More study would be great, but I believe it can clearly be medicinally beneficial, and has never killed anyone that used it- so it should be treated that way worldwide. I did not make the statement "weed cures cancer" but cannabinoids shrinking tumors is certainly worth talking about, especially if people want to be free to choose their own medicine. I want to see studies with human trials with various cannabinoids, and also human trials with juicing raw cannabis. I will openly admit some of that stuff is over my head, but more study and then a layman's version would be fantastic.
I believe the full understanding of the cannabinoid/health relationship will only develop after we are free. I strongly feel no anti-tumor agent should be illegal anywhere within the USA, and I think we will be free faster if this is openly discussed.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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I believe the full understanding of the cannabinoid/health relationship will only develop after we are free. I strongly feel no anti-tumor agent should be illegal anywhere within the USA, and I think we will be free faster if this is openly discussed.
I agree, that statement applies to everywhere on a global level, not just USA :)
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"No accepted medical value" but yet the FDA has patents on cannabidiol. Haha. Very hypocritical.
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Cannabinoids could be a safe alternative to chemotherapy <--- That is not medical advice.
Good thing, because it is not correct. If you read the study you will find that the real advantage of the utilization of adjuvant cannabinoids is that certain cell lines are particularly resistant to Gemcitibine. These show a marked increase in sensitivity to the drug with the addition of cannabinoids. Consequently, if you are unlucky enough to have that particular tissue type tumor, the addition of cannabinoids MAY help. Cannabinoids alone are most definitely NOT a safe alternative to chemotherapy!
Further reality check: This study was done in mice. While they are a good human analog, they are most decidedly NOT human, and AFAIK, there have not been any human trials showing any benefit... yet. This study, and others like it will most likely result in an eventual human trial. Because of ethical concerns, medicine has traditionally been, and will likely continue to be, one of the slowest progressing areas in all of science. :(
S.L.
Shpongle Lover,
I just noticed this post... I have read into a number of these studies, not just 1 (most are downloaded 1 time; idk who that 1 was).
Maybe I missed something, please enlighten me... I am aware that these studies are in mice and/or petri dishes. I am under the impression that studies of this using human cells in tissue culture have been done. I know this is not exactly the same as human trials. Dosage, route of administration, which cannabinoids, etc. may need more study, but I'm comfortable in what I have said so far.
I ask you to explain the comments "Good thing, because it is not correct." and "Cannabinoids alone are most definitely NOT a safe alternative to chemotherapy!"
If the bulk of this evidence suggests different than I am implying, I want to know.
I said may... and I stand by it so far.
I will openly admit some of that stuff is over my head, but please explain where I am wrong.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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http://m.youtube.com/watch?v=CdmcJFZSIP0
I posted this in the shoutbox... But just in case noone saw it
Its entitled "cannabis is a vegetable". And i believe it is, for the most part :)
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Although Seed Collector started the thread quoting the rules and stating his intention to comply with them, I want to give it a little bump with the reminder - discussion of preparation or consumption of illegal compounds is not allowed in the STS Rules, and in the case of Cannabis, discussion about gardening or trading seeds/live cuttings is not allowed.
Someone has expressed their concern that this thread might enter a grey area, so please keep that in mind.
Kind regards,
Mandrake
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I ask you to explain the comments "Good thing, because it is not correct." and "Cannabinoids alone are most definitely NOT a safe alternative to chemotherapy!"
If the bulk of this evidence suggests different than I am implying, I want to know.
I said may... and I stand by it so far.
I will openly admit some of that stuff is over my head, but please explain where I am wrong.
Sure, I'd be happy to elaborate. Cannabinoids are not cytotoxic. They do not kill cancer cells, and therefore they cannot be considered a treatment for any form of cancer in humans that I am aware of. Certainly not in pancreatic cancer, where the mortality rate is huge, usually greater than 80% at five years. There are, however, chemotherapeutic agents which DO kill cancer cells, and, if administered alone or in combination with surgery and/or adjuvant radiotherapy (ex: Hodgkins lymphoma or Pancoast tumor) actual cures are possible. Cannabinoids do not represent a treatment, and certainly have never been documented to have cured a single human of any form of malignancy.
Cannabis, in many of its forms certainly has a place in medicine. To say otherwise would deny a huge body of both anecdotal evidence and empiric, double-blind studies. If we are restricting ourselves to a discussion of cancer, the most commonly cited benefits include a reduction in nausea, increases appetite, and a "remoteness" from the pain of the cancer and the anxiety often attendant with a diagnosis of a terminal illness.
It would appear from the studies cited (so far I've only read two of them thoroughly) that neither propose SUBSTITUTING cannabinoids for a chemotherapeutic agent; rather, they suggest a possible benefit from a synergistic utilization of cannabinoids use ALONG WITH appropriate chemotherapeutic protocol agents. I'm fine with that. I think it deserves further study, and ought to be fast-tracked.
Studies such as those cited tend to cause cognitive dissonance amongst the policy makers. They are VERY used to viewing scheduled drugs as having no medical benefit. It is their mantra...the policy they hide behind to keep the prison industry and law enforcement afloat. You and I both know this is hogwash, but after 50 years and multiple billions of dollars spent on the drug war, and the wrongful incarceration of tens of thousands of US citizens, the likelihood of the politicians admitting they erred is about zero.
S.L.
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Maybe a combination of marijuana and tabernaemontana divaricata to fight cancer. just found this paper thought it was pretty interesting.
http://www.ajpcr.com/Vol5Suppl4/1309.pdf (http://www.ajpcr.com/Vol5Suppl4/1309.pdf)
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Maybe a combination of marijuana and tabernaemontana divaricata to fight cancer. just found this paper thought it was pretty interesting.
http://www.ajpcr.com/Vol5Suppl4/1309.pdf (http://www.ajpcr.com/Vol5Suppl4/1309.pdf)
When I tried to download this pdf, I recieved the message "pageok". Does the link work for you?
Edit: I've tried windows 7, and then I tried Tor.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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I opened it into a new tab then downloaded it just fine. Try a different browser.
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https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]
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http://www.alphagalileo.org/ViewItem.aspx?ItemId=135404&CultureCode=en (http://www.alphagalileo.org/ViewItem.aspx?ItemId=135404&CultureCode=en)
"Study shows non-hallucinogenic cannabinoids are effective anti-cancer drugs
14 October 2013 St George's, University of London
New research has shown that the non-hallucinogenic components of cannabis could act as effective anti-cancer agents.
The anti-cancer properties of tetrahydrocannabinol (THC), the primary hallucinogenic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited.
The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research.
The team, led by Dr Wai Liu and colleagues carried out laboratory investigations using a number of cannabinoids, either alone or in combination with each other, to measure their anti-cancer actions in relation to leukaemia.
Of six cannabinoids studied, each demonstrated anti-cancer properties as effective as those seen in THC. Importantly, they had an increased effect on cancer cells when combined with each other.
Dr Liu said: “This study is a critical step in unpicking the mysteries of cannabis as a source of medicine. The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising.
“These agents are able to interfere with the development of cancerous cells, stopping them in their tracks and preventing them from growing. In some cases, by using specific dosage patterns, they can destroy cancer cells on their own.
“Used in combination with existing treatment, we could discover some highly effective strategies for tackling cancer. Significantly, these compounds are inexpensive to produce and making better use of their unique properties could result in much more cost effective anti-cancer drugs in future.”
This latest research is part of a growing portfolio of studies into the medicinal properties of cannabis by the research team at St George’s. The next step will be to examine in the laboratory these compounds in combination with existing anti-cancer treatments and study treatment schedules to identify strategies that will maximise their efficacy.
The study examined two forms of cannabidiol (CBD), two forms of cannabigerol (CBG) and two forms of cannabigevarin (CBGV). These represent the most common cannabinoids found in the cannabis plant apart from THC."
Below is the paper's abstract & the pdf is attached to this post. http://www.ncbi.nlm.nih.gov/pubmed/24123005 (http://www.ncbi.nlm.nih.gov/pubmed/24123005)
"Anticancer Res. 2013 Oct;33(10):4373-80.
Enhancing the activity of cannabidiol and other cannabinoids in vitro through modifications to drug combinations and treatment schedules.
Scott KA, Shah S, Dalgleish AG, Liu WM.
Source
Dept of Oncology, Division of Clinical Sciences, St. George's, University of London, 2nd Floor, Jenner Wing, London, SW17 0RE, U.K. w.liu@sgul.ac.uk.
Abstract
Cannabinoids are the bioactive components of the Cannabis plant that display a diverse range of therapeutic qualities. We explored the activity of six cannabinoids, used both alone and in combination in leukaemic cells. Cannabinoids were cytostatic and caused a simultaneous arrest at all phases of the cell cycle. Re-culturing pre-treated cells in drug-free medium resulted in dramatic reductions in cell viability. Furthermore, combining cannabinoids was not antagonistic. We suggest that the activities of some cannabinoids are influenced by treatment schedules; therefore, it is important to carefully select the most appropriate strategy in order to maximise their efficacy.
KEYWORDS:
Cannabinoids, drug combination, drug schedule, leukaemia"
http://norml.org/news/2013/10/17/study-non-psychoactive-plant-cannabinoids-possess-synergistic-anti-cancer-activity-in-leukemia-cell-lines (http://norml.org/news/2013/10/17/study-non-psychoactive-plant-cannabinoids-possess-synergistic-anti-cancer-activity-in-leukemia-cell-lines) <--- NORML on the topic.
https://www.dropbox.com/home/Cannabis (https://www.dropbox.com/home/Cannabis)+https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar (https://www.dropbox.com/s/gkf42j1ttv2xr6t/Cannabis.rar)+https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip (https://www.dropbox.com/s/4l6cty9bxpnl7im/Cannabis.zip)
^ Cannabis and Cannabinoid Scientific Literature. [some keywords: cancer, apoptosis, and the word suffix "oma"]